They have advised doctors to give it intravenously, rather than through injections under the skin, noting that most of the cases of aplasia have been associated with injections.
42.
The American counterpart of Eprex, sold as Epogen by Amgen and as Procrit by Johnson & Johnson, is not linked to a high incidence of aplasia.
43.
Cutaneous lesions described in patients with CMTC include nevus flammeus, hemangioma, nevus anemicus, caf?au-lait spots, melanocytic nevus, aplasia cutis and acral cyanosis.
44.
Most affected people also experience eye problems, varying from colobomata of the lower eyelids and aplasia of lid lashes to short, down-slanting palpebral fissures, and missing eyelashes.
45.
Other possible symptoms of lissencephaly include telecanthus, estropia, hypertelorism, varying levels of mental retardation, cerebellar hypoplasia, corpus callosum aplasia, and decreased muscle tone and tendon reflexes.
46.
Studies in mice have shown that interfering with the HOX15 gene can cause parathyroid gland aplasia, which suggests the gene plays an important role in the development of the parathyroid gland.
47.
"' Paul Kaznelson "'( 1898 & ndash; 1959 ) was a Polish-born Czech scientist credited with describing the first case of pure red cell aplasia.
48.
In the patients with red cell aplasia, Mayeux found that antibodies treated the drug as a foreign protein _ and then did the same to the patient's natural EPO as well.
49.
In the meantime, Johnson & Johnson began to note red cell aplasia in patients taking competing products, including NeoRecormon, made by Roche, and Epogen, made by Amgen.
50.
About 175 people taking Eprex between 1998 and this April contracted a disease called pure red cell aplasia, according to a paper being published in The New England Journal of Medicine on Thursday.