HES is a diagnosis of exclusion, after clonal eosinophilia ( such as leukemia ) and reactive eosinophilia ( in response to infection, autoimmune disease, atopy, hypoadrenalism, tropical eosinophilia, or cancer ) have been ruled out.
42.
Numerous studies that used probiotics in different forms or sources such as supplemented formula, supplemented water, and capsule in which contents were mixed with food for treatment and management of atopy have associated with positive anti-inflammatory responses.
43.
The " CysLTR1 gene " product variant, 300G / S ( i . e . amino acid glycine replaces serine at the 300 position of the CysLTR1 protein ), has been shown to be significantly associated with atopy in this population.
44.
Increased intestinal permeability is a factor in several diseases, such as Crohn's disease, celiac disease, type 1 diabetes, type 2 diabetes, inflammatory bowel disease, schizophrenia, certain types of cancer, fatty liver, atopy and allergic diseases,
45.
Evidence has shown that exposure to food and fecal-oral pathogens, such as hepatitis A, " Toxoplasma gondii ", and " Helicobacter pylori " ( which also tend to be more prevalent in developing countries ), can reduce the overall risk of atopy by more than 60 %, and an increased rate of parasitic infections has been associated with a decreased prevalence of asthma.
46.
"' Eosinophilic granulomatosis with polyangiitis "'( "'EGPA "'; also known as "'Churg-Strauss syndrome [ CSS ] "'or "'allergic granulomatosis "') is a rare autoimmune condition that causes inflammation of small and medium-sized blood vessels ( vasculitis ) in persons with a history of airway allergic hypersensitivity ( atopy ).