| 41. | This suggests autophagy induction in gliomas could be caused by micro-environmental changes.
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| 42. | The mTOR pathway normally inhibits autophagy, as is induced by heightened glucose uptake.
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| 43. | Therefore, decreasing glucose levels should suppress the mTOR pathway, allowing for autophagy.
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| 44. | Autophagy is when a cell digests some of its own organelles by lysosomal degradation.
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| 45. | It strongly inhibits telomerase and stimulates multiple mechanisms including apoptosis, autophagy and senescence.
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| 46. | Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly.
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| 47. | Proteins involved in autophagy are reduced with age in both human and mouse articular cartilage.
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| 48. | These results suggest autophagy is a normal protective process ( chondroprotection ) in the joint.
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| 49. | The role of autophagy in cancer is one that has been highly researched and reviewed.
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| 50. | Moreover, Parkin is described to be necessary for mitophagy ( autophagy of mitochondria ).
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