Mutations in super-enhancers have been noted in various diseases, including cancers, type 1 diabetes, Alzheimer s disease, lupus, rheumatoid arthritis, multiple sclerosis, systemic scleroderma, primary biliary cirrhosis, Crohn s disease, Graves disease, vitiligo, and atrial fibrillation.
42.
He described aspects associated with a form of secondary biliary cirrhosis that was once referred to as " Hanot R�ssle syndrome " ( named in conjunction with French physician Victor Charles Hanot ( 1844 1896 ) ).
43.
The presence of AMA in the blood or serum of a person may be indicative of the presence of, or the potential to develop, the autoimmune disease primary biliary cirrhosis ( PBC; also known as primary biliary cholangitis ).
44.
They are a recognized feature of Wilson's disease ( 25 % ), primary biliary cirrhosis ( 24 % ), non-alcoholic cirrhosis ( 24 % ), hepatocellular carcinoma ( 23 % ) and morbid obesity ( 8 % ), among other conditions.
45.
Coeliac disease is associated with a number of other medical conditions, many of which are autoimmune disorders : diabetes mellitus type 1, hypothyroidism, primary biliary cirrhosis, microscopic colitis, gluten ataxia, psoriasis, vitiligo, autoimmune hepatitis, dermatitis herpetiformis, primary sclerosing cholangitis, and more.
46.
His research involved almost all areas of Hepatology, in particular portal hypertension, primary biliary cirrhosis, liver transplantation, hepatocellular carcinoma, liver fibrosis, coagulation in liver disease and the role of bacterial infections in liver disease . together with numerous editorials, book chapters and books.
47.
The authors of " The Autoimmune Connection " say that more than 50 million Americans, 75 percent of them women, are afflicted with these disorders that seem, on the surface, to have no connection with one another : rheumatoid arthritis, Crohn's disease, multiple sclerosis, primary biliary cirrhosis, psoriasis, underactive and overactive thyroid, and lupus, to name a few.
48.
"' Intercept Pharmaceuticals, Inc . "'is an American biopharmaceutical company incorporated in 2002, focusing on the development of novel synthetic bile acid analogs to treat chronic liver diseases, such as primary biliary cirrhosis ( PBC ), non-alcoholic fatty liver disease ( or non-alcoholic steatohepatitis, NASH ), cirrhosis, portal hypertension, primary sclerosing cholangitis and also the intestinal disorder, bile acid diarrhea.
