| 41. | This proposal provided a framework for understanding the evolution of biosynthetic pathways and presaged the study of molecular evolution.
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| 42. | Horowitz considered that repetition of such mutation / selection events formed the basis of the evolution of biosynthetic pathways.
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| 43. | Based on deuterium tracking studies, the biosynthetic pathway for aubucin from the cyclized lactone intermediate is organism specific.
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| 44. | Early work was done by Derek Barton and co-workers to illustrate the biosynthetic pathways towards erythrina alkaloids.
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| 45. | In 2016, the biosynthetic pathway of noscapine was reconstitued in yeast cells, allowing the drug to be synthesised.
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| 46. | These strains cannot synthesize adenine due to a nonsense mutation in one of the enzymes involved in the biosynthetic pathway.
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| 47. | The biosynthesis of tunicamycins was studied in " Streptomyces chartreusis " and a proposed biosynthetic pathway was characterized.
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| 48. | The shikimate pathway is a biosynthetic pathway that allows plants, fungi, and bacteria to produce aromatic amino acids.
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| 49. | This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway.
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| 50. | In " Arabidopsis thaliana ", a glycosyltransferase, UGT79B1, is involved in the anthocyanin biosynthetic pathway.
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