Presumably, vertebrates have this function to be able to detect a wide range of chemicals, indicated by the wide range of substrates Ahr is able to bind and facilitate their biotransformation and elimination.
42.
The water then trickles through a constructed wetland or " artificial reed bed ", where bioremediation bacterial action on the surface of roots and leaf litter removes some of the nutrients in biotransformation.
43.
Biocatalysis, a . k . a . biotransformation and bioconversion, makes use of natural or modified isolated enzymes, enzyme extracts, or whole-cell systems for enhancing the production of small molecules.
44.
The human CYP3A subfamily, CYP3A4, CYP3A5, CYP3A7 and CYP3A43, is one of the most versatile of the biotransformation systems that facilitate the elimination of drugs ( 37 % of the 200 most frequently prescribed drugs in the U . S.
45.
The metabolism of this compound in the body by means of biotransformation reactions is the key to its carcinogenicity . 2-AAF is a substrate for cytochrome P-450 ( CYP ) enzyme, which is a part of a super family found in almost all organisms.
46.
The elimination of a wide range of pollutants and wastes from the environment requires increasing our understanding of the relative importance of different pathways and regulatory networks to carbon flux in particular environments and for particular compounds, and they will certainly accelerate the development of bioremediation technologies and biotransformation processes.
47.
While toxicokinetics describes the changes in the concentrations of a toxicant over time due to the uptake, biotransformation, distribution and elimination of toxicants, toxicodynamics involves the interactions of a toxicant with a biological target and the functional or structural alterations in a cell that can eventually lead to a toxic effect.
48.
Inclusion of the allylic functions presented an enhanced potential area of biotransformation, and thus alcuronium is observed to have a much shorter duration of neuromuscular blocking action than its parent C-toxiferine I . It also has a more rapid onset of action, and is ~ 1.5 times as potent as tubocurarine.
49.
Study results published in The Journal of Nutrition outline the metabolism and mechanisms of action of cruciferous vegetable constituents, discusses human studies testing effects of cruciferous vegetables on biotransformation systems and summarizes the epidemiologic and experimental evidence for an effect of genetic polymorphisms ( genetic variations ) in these enzymes on response to cruciferous vegetable intake.
50.
Massive amounts of inorganic mercury were discovered in her brain, a fact which led researchers to conclude " Since inorganic mercury crosses the blood-brain barrier poorly, biotransformation of methyl to inorganic mercury may have occurred after methylmercury crossed the blood-brain barrier, accounting for its persistence in brain and causing part of the brain damage .
