In 1893 Emil Kraepelin borrowed the term from Schule and Pick and in 1899 introduced a broad new distinction in the classification of mental disorders between " dementia praecox " and mood disorder ( termed manic depression and including both unipolar and bipolar depression ).
42.
"' Cycloserine / lurasidone "'( proposed brand name "'Cyclurad "') is a combination formulation of cycloserine ( D-cycloserine ), a partial agonist of the glycine site of the NMDA receptor, and lurasidone, an atypical antipsychotic, which is under development for the treatment of bipolar depression by NeuroRx.
