The direct product of RuBP carboxylase reaction is glyceraldehyde-3-phosphate; these are subsequently used to make larger carbohydrates.
42.
Triheptanoin is used clinically in humans to treat inherited metabolic diseases, such as pyruvate carboxylase deficiency and carnitine palmitoyltransferase II deficiency.
43.
Furthermore, by using 1 ATP and bicarbonate, pyruvate will be converted to oxaloacetate . which is catalysed by pyruvate carboxylase.
44.
Pyruvate carboxylase was first discovered in 1959 at Western Reserve University by M . F . Utter and D . B . Keech.
45.
As a key role of gluconeogenesis is in the maintenance of blood sugar, deficiency of pyruvate carboxylase can also lead to hypoglycemia.
46.
Individuals with these multiple carboxylase disorders have the same problem with leucine catabolism as those with 3-methylcrotonyl-CoA carboxylase deficiency.
47.
Individuals with these multiple carboxylase disorders have the same problem with leucine catabolism as those with 3-methylcrotonyl-CoA carboxylase deficiency.
48.
The systematic name of this enzyme class is "'ATP : [ acetyl-CoA carboxylase ] phosphotransferase " '.
49.
The carboxylation reaction only proceeds if the carboxylase enzyme is able to oxidize vitamin K hydroquinone to vitamin K epoxide at the same time.
50.
Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis.
