The resulting activity shift in the biofilm ( and resulting acid production within the biofilm, at the tooth surface ) is associated with an imbalance between demineralization and remineralisation leading to net mineral loss within dental hard tissues ( enamel and then dentin ), the sign and symptom being a carious lesion.
42.
Tertiary dentin is only formed by an odontoblast directly affected by a stimulus; therefore, the architecture and structure depend on the intensity and duration of the stimulus, e . g ., if the stimulus is a carious lesion, there is extensive destruction of dentin and damage to the pulp, due to the differentiation of bacterial metabolites and toxins.
43.
Four clinical sessions, with a 1-week interval, are performed, so the dentist is able to act over causal factors ( instructing parents ), to increase tooth resistance ( hygiene with diluted H 2 O 2 solution and gauze; application of fluoride varnish over white spot lesions and softened carious lesions ), as well as to restore tooth cavities with glass ionomer cement ( Atraumatic Restorative Treatment ).
44.
In 1743 he published the paper " On the structure and diseases of articulating cartilages " which is often cited especially the following sentence : If we consult the standard Chirurgical Writers from Hippocrates down to the present Age, we shall find, that an ulcerated Cartilage is universally allowed to be a very troublesome Disease; that it admits of a Cure with more Difficulty than carious Bone; and that, when destroyed, it is not recovered .
45.
Holding age ( all participants were between 14 and 16 ) and IQ ( average of 77 ) constant, the boys were tested to determine whether there are : ( 1 ) differences in competency to respond to concrete situations as measured by standardized tests; ( 2 ) differences in emotional stability and tendencies toward problem behavior as measured by personality tests; ( 3 ) differences in social maturity as measured by a social maturity scale; ( 4 ) relationships among the carious tests administered, and ( 5 ) differences as determined through a questionnaire ( Watts, 1941, 192 ).
