Romantic rejection is a painful, emotional experience that appears to trigger a response in the caudate nucleus of the brain, and associated dopamine and cortisol activity.
42.
The main components of the basal ganglia are the caudate nucleus, the putamen, the globus pallidus, the substantia nigra, the nucleus accumbens, and the subthalamic nucleus.
43.
As such, many studies have correlated the loss of dopaminergic neurons that send axons to the caudate nucleus and the degree of dementia in Parkinson's patients.
44.
The direction of complex movement is based from the substantia nigra to the putamen and caudate nucleus, which then relay signals to the rest of the brain.
45.
Reports of human patients with selective damage to the caudate nucleus show unilateral caudate damage resulting in loss of drive, obsessive-compulsive disorder, stimulus-bound perseverative behavior, and hyperactivity.
46.
Patients who respond positively to serotonin reuptake inhibitors like Prozac or Luvox, the usual medications of choice, also show a lessening of activity in the caudate nucleus.
47.
The " motor release " observed as a result of this procedure indicates that the caudate nucleus inhibits the tendency for an animal to move forward without resistance.
48.
In a study involving rats given water-maze training, the caudate nucleus was discovered to enhance memory of visually cued training after amphetamine was infused post-training into the caudate.
49.
The prefrontal cortex is necessary but not solely sufficient for executive functions; for example, the caudate nucleus and subthalamic nucleus also have a role in mediating inhibitory control.
50.
Brain imaging that uses PET scans, or positron emission topography, has shown that the disorder is associated with functional hyperactivity of the caudate nucleus, a structure buried beneath the cerebral cortex.
