| 41. | By catalyzing actin polymerization and stabilizing microtubules, mDia1 plays also an important role for cell migration.
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| 42. | Potentially this gene is suppressing cell migration or invasion, and keeping the cell in one place,
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| 43. | Dynamic microtubules are needed for the cell migration that underlies processes such as tumor metastasis and angiogenesis.
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| 44. | The dynamics are normally suppressed by low, subtoxic concentrations of microtubule drugs that also inhibit cell migration.
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| 45. | Its main components are fibronectin and hyaluronan, which create a very hydrated matrix and facilitate cell migration.
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| 46. | Eukaryotic cell migration typically is far more complex and can consist of combinations of different migration mechanisms.
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| 47. | This means that it is able to control different cell migration programs specific to different types of cells.
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| 48. | Suppression of microtubule dynamics by tubulin mutations or by drug treatment have been shown to inhibit cell migration.
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| 49. | A recent in vitro study in 2008 has found that OPN plays a role in mast cell migration.
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| 50. | Her research into cell migration is soon to be published and has implications for cancer treatment, Gertler said.
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