""'Amphidromus coeruleus " "'is a species of air-breathing land snail, a terrestrial pulmonate gastropod mollusk in the family Camaenidae.
42.
Norepinephrine ( NE ) is released by the Locus coeruleus, it is then transferred to the limbic system where much of the memory consolidation and fight or flight responses are facilitated.
43.
This supersensitivity of ? 2-adrenoceptor was postulated to decrease locus coeruleus ( the main projection site of NA in the central nervous system, CNS ) NA activity leading to depression.
44.
According to the LC-NE hypothesis, when a salient, or meaningful stimulus is presented, neurons in the locus coeruleus release norepinephrine, a neurotransmitter that benefits the detection of the stimulus.
45.
Third, decreased size of the locus coeruleus, decreased activity of tyrosine hydroxylase, increased density of alpha-2 adrenergic receptor, and evidence from rat models suggest decreased adrenergic neurotransmission in depression.
46.
In Parkinson's disease, a disorder that affects neuromotor functioning, there is decreased neuromelanin in the substantia nigra and locus coeruleus as consequence of specific dropping out of dopaminergic and noradrenergic pigmented neurons.
47.
Regions in the brainstem that are not involved in visual perception also project to the LGN, such as the mesencephalic reticular formation, dorsal raphe nucleus, periaqueuctal grey matter, and the locus coeruleus.
48.
It directly acts on the paraventricular nucleus to decrease CRH release and down regulate norepinephrine functioning in the locus coeruleus . which is approximately the same amount of time it takes for SSRIs to take effect.
49.
In adult humans ( 19-78 ) the locus coeruleus has 22, 000 to 51, 000 total pigmented neurons that range in size between 31, 000 and 60, 000 ?m 3.
50.
The neurons in the locus coeruleus produce noradrenaline, as fore the neurons in the dorsal and median raphe nuclei, ventral periaqueductal grey matter, and tuberomammillary nucleus produce serotonin, dopamine and histamine respectively.
