This motif occurs in coiled coil motifs to maintain and reach a 20 degree " left hand crossing angle that is characteristic of coiled coils ".
42.
The proteins are predicted to form extended rods composed of 2 alpha-helical segments ( ~ 180 residues long ) capable of forming coiled coils, interrupted by non-helical linkers.
43.
Each molecule of gp41, they found, contains a spiral region, and in the HIV knob three of these spirals entwine, forming a braidlike structure called a coiled coil.
44.
It was recently demonstrated by Peacock and co-workers that coiled coils may be self-assembled using lanthanide ( III ) ions as a template, thus producing novel imaging agents.
45.
When the tip of the knob, gpl20, latches onto the immune cell's receptors, it flips back like the lid on a tin can, releasing the coiled coil within.
46.
Secondary structure prediction involves a set of methods in bioinformatics that aim to predict the transmembrane helixes and coiled coils in proteins, or canonical micro-RNA structures in RNA.
47.
Mercury on the other hand was found to bind to two sulfur atoms in separate peptides via a linear shape, thus causing the formation of a two strand coiled coil.
48.
Coiled coils have been found in flu viruses, and their use in HIV which is not related to influenza makes Chan and Kim suspect this is a common viral ploy.
49.
Interestingly, NBPF1 seems to be involved in proliferation during human neurogenesis, and growth suppression during adulthood, showing that the DUF1220 and coiled coil domains may be important during different life stages.
50.
The encoded protein is composed solely of a BAR domain which is predicted to form coiled coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases.
