In such autoimmune diseases, the body's defense system typically turns against itself by honing in and destroying one of the body's proteins, and some scientists have proposed that rheumatoid arthritis attacks collagen, a fibrous protein found in cartilage, bone and connective tissues, but the evidence has been ambiguous.
42.
Recently approved by the US Food and Drug Administration, the artificial skin consists of a two-layer membrane : one is made up of collagen, a fibrous protein from animal tendons and animal cartilage, and the other of silicone rubber called silastic, which is eventually peeled off as the wound heals and replaced with a thin layer of the patient's own skin.
43.
These enzymes have wide range of substrate specificity such as it can degrade other fibrous protein fibrin, elastin, collagen and other non fibrous protein like casein, bovine serum albumin gelatin etc . ( Noval et al ., 1959; Mukhapadhayay et al ., 1989; Dozie et al ., 1994; Lin et al ., 1995; Letourneau et al ., 1998; and Bressollier et al ., 1999 ).
44.
These enzymes have wide range of substrate specificity such as it can degrade other fibrous protein fibrin, elastin, collagen and other non fibrous protein like casein, bovine serum albumin gelatin etc . ( Noval et al ., 1959; Mukhapadhayay et al ., 1989; Dozie et al ., 1994; Lin et al ., 1995; Letourneau et al ., 1998; and Bressollier et al ., 1999 ).
