This gene encodes a flavoprotein oxidoreductase that binds single stranded DNA and is thought to contribute to apoptosis in the presence of bacterial and viral DNA . The expression of this gene is also found to be induced by tumor suppressor protein p53 in colon cancer cells.
42.
Her laboratory focused on proteins involved in electron and group transfer reactions; over the next four decades it solved, amongst others, the structures of flavodoxin, the first flavoprotein structure, iron-superoxide dismutase, p-hydroxybenzoate hydroxylase and phthalate dioxygenase reductase.
43.
The first mention of a flavoprotein in the scientific literature dates back to 1879, when the work on the composition of cow s milk resulted in the isolation of a bright-yellow pigment, that we now know as flavin, but termed lactochrome at the time.
44.
Mutations in the " ETFA ", " ETFB ", and " ETFDH " genes cause glutaric acidemia type II . Glutaric acidemia type 2 is caused by a deficiency in either of two enzymes, called electron transfer flavoprotein and electron transfer flavoprotein dehydrogenase.
45.
Mutations in the " ETFA ", " ETFB ", and " ETFDH " genes cause glutaric acidemia type II . Glutaric acidemia type 2 is caused by a deficiency in either of two enzymes, called electron transfer flavoprotein and electron transfer flavoprotein dehydrogenase.
