"' Glutathione peroxidase "'( GPx ) ( ) is the general name of an enzyme family with peroxidase activity whose main biological role is to protect the organism from oxidative damage.
42.
This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense ( stop ) codon TGA.
43.
Like CMX-1152, the herbal version of Protandim that supplanted it was marketed by Lifeline as an " anti-aging " supplement that increases the body s antioxidant defenses by upregulating superoxide dismutase, catalase, and glutathione peroxidase.
44.
Of particular note in the excretion of arsenic is the multiple methylation steps that take place which may increase the toxicity of arsenic due to MMeAsIII being a potent inhibitor of glutathione peroxidase, glutathione reductase, pyruvate dehydrogenase, and thioredoxin reductase.
45.
He has experience in Organic synthesis, acting on the following topics : Green Chemistry, Asymmetric Catalysis, organoselenium bioactive molecules and selenium and tellurium derived amino acids and other natural products, Synthesis of the seleno-enzyme glutathione peroxidase mimetic.
46.
Generally, this treatment did not result in significant alterations in biochemical or hematological parameters, nor in relative organ weights, but some changes were noted in glutathione ( GSH ) concentration, and in the activity of glutathione peroxidase ( GPx ).
47.
Because free radicals are necessary for life, the body has a number of mechanisms to minimize free-radical-induced damage and to repair damage that occurs, such as the enzymes superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase.
48.
Reactive oxygen free radical species in the heart were quantified by the cytotoxic aldehydes malondialdehyde ( MDA ), 4-hydroxy-nonenal ( HNE ) and hexanal, while antioxidant reserve status was quantified by glutathione ( GSH ) and glutathione peroxidase ( GPx ) activity in the heart tissue.
49.
Results showed that the effects of WPC on the glutathione peroxidase and glutathione in the PB, the T and B cells in the spleen, and the B cells in the BM were more apparent in the rats with alcohol intake; however, they are not apparent in the controls.
50.
The researchers in this group, however, did not look towards as the proposed antioxidant function of Bcl-2 as being the underlying cardioprotective mechanism, instead suggesting that the enhancement of the expression of MnSOD, glutathione peroxidase, and catalase was the mechanism for the attenuation of apoptosis.
