Furthermore, dydrogesterone does not undergo 17?-hydroxylation, which may contribute to its lack of androgenic effects.
42.
The major metabolic reaction is aromatic hydroxylation to form 4 hydroxyphenformin, which is then conjugated with glucuronic acid.
43.
HIF1A activity is regulated by a host of post-translational modifications : hydroxylation, acetylation, and phosphorylation.
44.
Both the Holton Taxol total synthesis and the Wender Taxol total synthesis feature asymmetric ?-hydroxylation with camphorsulfonyloxaziridine.
45.
Carbamate groups are hydrolyzed to produce phenols and the " N "-methyl group undergoes hydroxylation.
46.
This suggests that the vicinal oxygenations at C-1 and C-2 are independent steps involving hydroxylation.
47.
In terms of molecular mechanisms, the enzyme facilitates the intramolecular hydroxylation of one meso carbon centre in the heme.
48.
This precludes the bidentate coordination complex necessary for di-phenolate hydroxylation characteristic of tyrosinase but absent in catechol oxidase.
49.
In the normal cell with active VHL protein, HIF alpha is regulated by hydroxylation in the presence of oxygen.
50.
MCPP is metabolized via the CYP2D6 isoenzyme by hydroxylation to p-hydroxy-mCPP ( OH-mCPP ).
