The symptoms of Ichthyosis hystrix Curth-Macklin are similar to epidermolytic hyperkeratosis ( NPS-2 type ) but there is no blistering and the hyperkeratosis is verrucous or spine-like.
42.
When a biopsy is done, hyperkeratosis, atrophic epidermis, sclerosis of dermis and lymphocyte activity in dermis are histological findings associated with LS . The biopsies are also checked for signs of dysplasia.
43.
Therefore, the typical pathologic features of canine distemper include lymphoid depletion ( causing immunosuppression and leading to secondary infections ), interstitial pneumonia, encephalitis with demyelination, and hyperkeratosis of the nose and foot pads.
44.
People with PS-type epidermolytic hyperkeratosis have thick skin on the palms of their hands and soles of their feet ( palmoplantar or palm / sole hyperkeratosis ) in addition to other areas of the body.
45.
People with PS-type epidermolytic hyperkeratosis have thick skin on the palms of their hands and soles of their feet ( palmoplantar or palm / sole hyperkeratosis ) in addition to other areas of the body.
46.
Pathomorphologic study of tissue sampling revealed : polymorphism of spiny epithelial cells has progressed into atypism; increased mitosis; giant and multinucleate cells; acanthosis; hyperkeratosis and parakeratosis; basal membrane and basal layer are retained.
47.
One type is characterized by generalized, persistent, brown hyperkeratosis with accentuated skin markings, while a second type is localized, with involvement that is limited in extent and characterized by sharply demarcated, hyperkeratotic plaques.
48.
Frogs infected by this disease generally show skin lesions and hyperkeratosis, and it is believed that death occurs because of interference with skin functions including maintenance of fluid balance, electrolyte homeostasis, respiration and role as a barrier to infections.
49.
A skin abnormality known as acanthosis nigricans, which involves a discoloration ( hyperpigmentation ) and velvety thickening ( hyperkeratosis ) of the skin around skin fold regions of the neck, groin and under arms is also a common symptom.
50.
Skin care with moisturizers can help prevent palmar and plantar hyperkeratosis and cracking and secondary risk of infection; neurotrophic keratitis is best treated with routine care for dry eyes, prevention of corneal infection, and daily observation of the ocular surface.