ImmunoGen said its product, called C242-DM1 proved more effective than 5-FU, the most common drug used to treat colon cancer.
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We can define an immunogen as a complete antigen which is composed of the macromolecular carrier and epitopes ( determinants ) that can induce immune response.
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Sanaria's initial candidate vaccine is called Sanaria Superscript textR PfSPZ, and uses radiation attenuated " Plasmodium falciparum " sporozoites as immunogen.
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ImmunoGen, whose research pedigree is from Boston's Dana-Farber Cancer Institute, was among the first generation of Boston-area biotech firms.
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After the antibody is purified from the milk, Cambridge's ImmunoGen said it would couple the antibody with a drug to develop the cancer treatment.
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But ImmunoGen has developed a way to attach the drug to monoclonal antibodies, molecules known for their ability to seek out specific disease-causing cells.
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An immunogen is a substance ( or adduct ) that is able to trigger a humoral ( innate ) and / or cell-mediated immune response.
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Therefore, by exposing an animal to an immunogen in a controlled way, its body can learn to protect itself : this is called active immunization.
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This can be resolved by absorption of these antibodies with their cross-reactive antigen, leaving only the antibodies that are specific to the immunogen of interest.
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:When I looked at our antigen article, I saw it distinguishes between antigens and immunogens; it looks like the medline article is just discussing immunogens.
