Cyclothiazomycin A contains a dehydroalanine and two dehydrohomoalanine residues within a bicyclic, macrocyclic scaffold composed of thiazolines, thiazoles, and a trisubstituted pyridine.
42.
Trost's route to the macrocyclic core of roseophilin, like others, relied on a Paal Knorr Pyrrole synthesis to obtain the fused pyrrole.
43.
Moreover, the flexibility of the linker chains allows the seven-membered rings to twist relative to each other as the macrocyclic ring size expands.
44.
The " P . monoica " life cycle is macrocyclic, including the production of basidia, telia, spermatia, aecia, and uredia.
45.
Effective treatments include the macrocyclic lactones, notably ivermectin or moxidectin, which can kill the early larval stages before they migrate into the liver and lungs.
46.
Moreover, levamisole and several macrocyclic lactones ( e . g . abamectin, doramectin, eprinomectin, ivermectin, moxidectin ) are reported to be effective.
47.
"' Telomestatin "'is a macrocyclic chemical compound that acts by inhibiting the telomerase activity of " in vitro " cancer cells.
48.
These transformations set the stage for the introduction of both epoxide groups, which were formed with high levels of diastereoselectivity based on the principles of macrocyclic stereocontrol.
49.
Ivermectin and other avermectins ( insecticides most frequently used in home-use ant baits ) are macrocyclic lactones derived from the bacterium " Streptomyces avermitilis ".
50.
Glycouril itself and derivatives of it are used as monomers for producing the macrocyclic cucurbiturils polymers, which serve as hosts to bind to various neutral and anionic species.
