| 41. | In contrast to the sexual diploids, the pairing of chromosomes at metaphase I in triploid apomicts is strongly reduced.
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| 42. | Griseofulvin inhibits fungal cell mitosis via disruption of the mitotic spindle structure and preventing cell division at the metaphase stage.
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| 43. | The new equatorial metaphase plate is rotated by 90 degrees when compared to meiosis I, perpendicular to the previous plate.
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| 44. | Look at the description of the figure " Diagram of a duplicated and condensed ( metaphase ) eukaryotic chromosome . ".
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| 45. | In yeast at the metaphase-to-anaphase transition, Scc1 dissociates from the chromosomes and the sister chromatids separate.
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| 46. | Cyclin A is degraded early in mitosis, supporting the theory, but cyclin B and securin are not degraded until metaphase.
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| 47. | Regulation of APC / C Cdc20 activity towards metaphase substrates like securin and cyclin B may be a result of intracellular localization.
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| 48. | The nuclear membrane does not disappear, but during metaphase the chromosomes are condensed, often considerably more than in normal mitosis.
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| 49. | The regulation of mammalian ORC is consistent with the removal of at least part of the complex from the chromosome at metaphase.
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| 50. | The phosphorylation of Cdc20 ultimately leads to decreased activity of APC / C which determines the metaphase-to-anaphase transition.
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