"Datura " intoxication typically produces delirium ( as contrasted to hallucination ), hyperthermia, tachycardia, bizarre behavior, and severe mydriasis with resultant painful photophobia that can last several days . Pronounced amnesia is another commonly reported effect.
42.
"Anticholinergic " : Paralytic ileus; hyperpyrexia; urinary retention, delayed micturition, dilatation of the urinary tract; constipation; blurred vision, disturbance of accommodation, increased intraocular pressure, mydriasis; dry mouth and rarely associated sublingual adentitis.
43.
Datura intoxication typically produces a complete inability to differentiate reality from fantasy ( delirium, as contrasted to hallucination ); hyperthermia; tachycardia; bizarre, and possibly violent behavior; and severe mydriasis with resultant painful photophobia that can last several days . Pronounced amnesia is another commonly reported effect.
44.
While oenanthotoxin is extremely dangerous and toxic ( LD 50 = 0.58 mg / kg for mice ), there have been numerous case studies documenting the common symptoms including : convulsions, seizures, nausea, diarrhea, tachycardia, mydriasis, rhabdomyolysis, renal failure, respiratory impairment, and cardiac dysrhythmias.
45.
In some cases there may be an asymptomatic phase following the initial symptoms which is then followed by more significant toxicity including kidney damage, Cases of severe poisoning may progress to a terminal neurological phase, with delirium, muscle fasciculations and seizures, and mydriasis progressing to coma, circulatory collapse, and respiratory arrest.
46.
It is incorrect to think that physiological signs such as increased heart rate ( tachycardia ), blood pressure ( hypertension ), dilation of the pupils ( mydriasis ), sweating ( diaphoresis ), and the formation of tears ( lacrimation ) will continue to occur normally in response to pain in the anesthetized state.
47.
Side effects such as unconsciousness or coma, hyperemesis, nausea, seizures, convulsions, tachycardia, bradycardia, mydriasis, syncope, spontaneous urinating and defecating, shortness of breath, somnolence, respiratory acidosis, metabolic acidosis, collapse, lower limbs paralysis, chest pain, aggression and severe disturbance of behaviour were reported.
48.
Clinical reports of the effects of consumption of " Mandragora autumnalis " include severe symptoms similar to those of atropine poisoning, including blurred vision, dilation of the pupils ( mydriasis ), dryness of the mouth, difficulty in urinating, dizziness, headache, vomiting, blushing and a rapid heart rate ( tachycardia ).
49.
Clinical reports of the effects of consumption of " Mandragora officinarum " ( as " Mandragora autumnalis " ) include severe symptoms similar to those of atropine poisoning, including blurred vision, dilation of the pupils ( mydriasis ), dryness of the mouth, difficulty in urinating, dizziness, headache, vomiting, blushing and a rapid heart rate ( tachycardia ).
50.
Due to the potent combination of anticholinergic substances it contains, " Datura " intoxication typically produces effects similar to that of an anticholinergic delirium ( usually involving a complete inability to differentiate reality from fantasy ); hyperthermia; tachycardia; bizarre, and possibly violent behavior; and severe mydriasis ( dilated pupils ) with resultant painful photophobia that can last several days . Pronounced amnesia is another commonly reported effect.
