| 41. | This PTP also suppresses JAK kinases, and, thus, functions as a negative regulator of cytokine receptor signaling.
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| 42. | Adapter molecule crk is a member of an C-terminal SH3 domain functions as a negative regulator of transformation.
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| 43. | The encoded protein acts as a dominant-negative regulator of transcription of other nuclear receptors including steroidogenic factor 1.
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| 44. | It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression.
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| 45. | This loop contains both positive regulators, which increase gene expression, and negative regulators, which decrease gene expression.
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| 46. | The IRA domains are hypothesized to function as negative regulators of RAS, along with the GRD domain in between them.
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| 47. | Regulatory genes can also be described as positive or negative regulators, based on the environmental conditions that surround the cell.
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| 48. | TRAF1 also functions as a negative regulator of inflammation by interfering with the linear ubiquitination of NEMO downstream of TLR signaling.
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| 49. | The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription.
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| 50. | The drug targeted an immune checkpoint called CTLA-4, known as a key negative regulator of T cell activity.
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