The wall of the neural tube consists of neuroepithelial cells, which differentiate into neuroblasts, forming the mantle layer ( the gray matter ).
42.
In neuroblasts, both complexes are localized to the apical cortex, causing apical / basal cell division and daughter cells exhibiting strong size asymmetry.
43.
Cell death in arthropods occurs first in the nervous system when ectoderm cells differentiate and one daughter cell becomes a neuroblast and the other undergoes apoptosis.
44.
In drosophila, neuroblasts divide asymmetrically, so that one product is a " ganglion mother cell " ( GMC ), and the other is a neuroblast.
45.
In drosophila, neuroblasts divide asymmetrically, so that one product is a " ganglion mother cell " ( GMC ), and the other is a neuroblast.
46.
In the mammalian fetal development ( fourth to fifth week in humans ), neuroblast cells migrate from the neural crest to form the sympathetic chain and preaortic ganglia.
47.
The vital differentiating proteins that are segregated into the daughter neuroblast and not the GMC are Bazooka, aPKC, Inscutable, and Partner of Inscutable ( Pins ).
48.
In clonal lines of neuroblasts that had been manipulated so that they lacked Lgl activity, Miranda did not segregate asymmetrically, but was evenly distributed throughout the cortex.
49.
FasII is also expressed by clusters of differentiating neuroblasts at early stages of neurogenesis where its function is not fully understood but might be involved in proneural gene induction.
50.
Hyperchromatic and bizarre nuclei in neuroblasts and ganglion cells in undifferentiated or poorly differentiated foci are far too pathognomonic, although anaplastic expressions can be found in differentiating foci alike.
