Neurotoxic effects have also been linked to poisoning with OP pesticides causing four neurotoxic effects in humans : cholinergic syndrome, intermediate syndrome, organophosphate-induced delayed polyneuropathy ( OPIDP ), and chronic organophosphate-induced neuropsychiatric disorder ( COPIND ).
42.
Many non-governmental and research groups, as well as the EPA's Office of Inspector General, have published concerns that the review did not take into account possible neurotoxic effects on developing fetuses and children, an area of developing research.
43.
"' Phenylahistin "'is a metabolite produced by the fungus " Aspergillus ustus " that belongs to a class of naturally occurring 2, 5-diketopiperazines featuring a dehydrohistidine residue that exhibit important biological activities, such as anti-cancer or neurotoxic effects.
44.
However, clinical studies have shown no signs of neurotoxic effects, and studies of metabolism suggest it is not possible to ingest enough aspartic acid and glutamate through food and drink to levels that would be expected to be toxic.
45.
The United States Environmental Protection Agency finished a 10-year review of the organophosphate pesticides following the 1996 Food Quality Protection Act, but did little to account for developmental neurotoxic effects, drawing strong criticism from within the agency and from outside researchers.
46.
This work was responsible for creating the classification of fetal alcohol syndrome; a disease characterized by common morphogenesis aberrations such as defects in craniofacial formation, limb development, and dietary vitamin E results in reduced or eliminated ethanol-induced neurotoxic effects in fetuses.
47.
They are also very similar to serotonin-norepinephrine-dopamine releasing agents ( SNDRAs ) like MDMA ( " ecstasy " ) and ?-ethyltryptamine ( ?ET ) for the same reason, although they act via a different psychedelic, and neurotoxic effects of SNDRAs like MDMA and ?ET.
48.
The WHO has classified the reported symptoms into broad categories, including : mucous membrane irritation ( eye, nose, and throat irritation ), neurotoxic effects ( headaches, fatigue, and irritability ), asthma and asthma-like symptoms ( chest tightness and wheezing ), skin dryness and irritation, gastrointestinal complaints and more.
49.
"People contemplating using Ecstasy should be aware it can damage brain cells and should recognize that its neurotoxic effects are likely to occur after doses commonly used in recreational settings, " said Dr . George Ricaurte, a neurologist at Johns Hopkins University School of Medicine in Baltimore and lead investigator of the study.
50.
Advocates of a thiomersal-autism link also relied on indirect evidence from the scientific literature, including analogy with neurotoxic effects of other mercury compounds, the reported epidemiologic association between autism and vaccine use, and extrapolation from " in vitro " experiments and animal studies Studies conducted by Mark Geier and his son David Geier have been the most frequently cited research by parents advocating a link between thiomersal and autism.
