| 41. | GDF2 induces the differentiation of mesenchymal stem cells ( MSCs ) to an osteoblast lineage.
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| 42. | It induces human osteoblast differentiation through extracellular signal-regulated kinase 1 / 2 pathway.
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| 43. | But in osteoporosis, the osteoblasts can't keep pace with the bone-destroyers.
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| 44. | The osteoblast cell forms new bone, while osteoclast dissolves old and worn out bone tissue.
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| 45. | Osteoblasts are responsible for bone formation.
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| 46. | Unlike the much larger osteoclasts, osteoblasts are much smaller; they only have one nucleus.
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| 47. | Osteoblasts are important because they allow the bones to be made, remodeled, and repaired.
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| 48. | Osteoblasts create bone and osteoclasts destroy it, especially if force is placed on a tooth.
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| 49. | Bone is resorbed by osteoclasts, and is deposited by osteoblasts in a process called ossification.
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| 50. | Rodan researched the connection between osteoblasts and osteoclasts and helped to analyse and describe the two.
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