Diagnosis depends on the combination of developmentally inappropriate severe overactivity, motor stereotypies, and moderate to severe intellectual disability; all three must be present for the diagnosis.
42.
This toxin may be of value in the treatment of urinary bladder overactivity, stroke treatment and in problems with the hyperactivity of ( vascular ) smooth muscle cells.
43.
While deregulation of either of these pathways can disturb motor output, hyperkinesia is thought to result from overactivity of the direct pathway and decreased activity from the indirect pathway.
44.
In particular, the dopamine hypothesis of psychosis has been influential and states that psychosis results from an overactivity of dopamine function in the brain, particularly in the mesolimbic pathway.
45.
The resulting overactivity of FGF-23 reduces vitamin D 1?-hydroxylation and phosphate reabsorption by the kidneys, leading to hypophosphatemia and the related features of hereditary hypophosphatemic rickets.
46.
It is unknown why males are predominantly affected, with rates in males being 17-to 70-fold those in females, despite thyroid overactivity being much more common in women.
47.
The overactivity and underactivity in these different regions may be linked, and may not be due to a primary dysfunction of dopamine systems but to more general neurodevelopmental issues that precede them.
48.
There is extensive experience, over many years, of the use of radioiodine in the treatment of thyroid overactivity and this experience does not indicate any increased risk of thyroid cancer following treatment.
49.
Brain scans of nine migraine patients, studied within six hours of the start of migraine attacks, showed persistent overactivity in a structure called the brainstem at the base of the brain, researchers report.
50.
"' Antillatoxin "'( "'ATX "') is a potent lipopeptide neurotoxin produced by the marine NMDA-receptor overactivity, excess calcium influx and neuronal necrosis.
