The chemically determined amino acid sequence revealed that chicken H-protein is composed of 125 amino acids with a lipoic acid prosthetic group at lysine 59 ( Lys59 ).
42.
If it is oxidized, the band has a length of 636 nm, and a 638 nm length if it is prosthetic groups when found in multiple subunit complexes.
43.
Finally, the active site contains a heme prosthetic group in which the iron is tethered to a thiolate ligand on a conserved cysteine residue ( Lepesheva et al . ).
44.
Here, acetyltransferase transfers the acetate group from acetyl-CoA onto the SH group of the 42-phosphopantetheine prosthetic group of ACP, which had been attached during activation.
45.
Organic cofactors can be either coenzymes, which are released from the enzyme's active site during the reaction, or prosthetic groups, which are tightly bound to an enzyme.
46.
Methylmalonyl-CoA mutase catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, and uses a B12 derived prosthetic group, adenosylcobalamin, in order to accomplish this transfer.
47.
Rather, near-UV CD spectra provide structural information on the nature of the prosthetic groups in proteins, e . g ., the heme groups in hemoglobin and cytochrome c.
48.
A 1979 letter in " Trends in Biochemical Sciences " noted the confusion in the literature and the essentially arbitrary distinction made between prosthetic groups and coenzymes and proposed the following scheme.
49.
In addition, both NOS1 and NOS2 have been shown to form ferrous-nitrosyl complexes in their heme prosthetic groups that may act partially to self-inactivate these enzymes under certain conditions.
50.
The reaction is performed by the 42-phosphopantetheine prosthetic group of CoA to the acyl carrier protein ( ACP ) domain, which is found in the N terminus of the ? subunit.