In recognition of his contributions to the study of vitamin B6 biochemistry, the 1999 meeting in a regular series of international symposia on pyridoxal catalysis was dedicated to Snell.
42.
Transaminases require the coenzyme pyridoxal-phosphate, which is converted into pyridoxamine in the first phase of the reaction, when an amino acid is converted into a keto acid.
43.
The reaction requires pyridoxal 5'- phosphate as a co-factor and forms part of the subpathway that synthesizes L-glutamate 5-semialdehyde from L-ornithine.
44.
Its toxicity stems primarily from the fact that it readily forms oximes with keto acids and aldehydes, especially the pyridoxal phosphate cofactor of many vitamin B 6-dependent enzymes.
45.
In molecular biology, "'group III pyridoxal-dependent decarboxylases "'are a family of bacterial enzymes comprising ornithine decarboxylase, lysine decarboxylase and arginine decarboxylase.
46.
Glycogen phosphorylase has a pyridoxal phosphate ( PLP, derived from S N 1 fashion, resulting in the formation of a glucose molecule with a secondary carbocation at the 1 position.
47.
In each of the 19 pathways for the generation of chiral amino acids, the stereochemistry at the ?-carbon atom is established by a transamination reaction that involves pyridoxal phosphate.
48.
CBS uses the cofactor pyridoxal-phosphate ( PLP ) and can be allosterically regulated by effectors such as the ubiquitous cofactor S-adenosyl-L-methionine ( adoMet ).
49.
The mutations T67I and Q240E weaken the enzyme's affinity for pyridoxal phosphate, the co-factor vital to enzymatic function . Propargylglycine ( acidic beta hydrogen explicitly shown ).
50.
Pyridoxal is involved in what is believed to be the most ancient reaction of aerobic metabolism on Earth, about 2.9 billion years ago, a forerunner of the Great Oxidation Event
