The source of the cells in epiretinal membranes ( ERM ) has been found to comprise glial cells, retinal pigment epithelial ( RPE ) cells, macrophages, fibrocytes, and collagen cells.
42.
One example is the transformation of lens cells in the process of maturation and transformation of retinal pigment epithelium cells into the neural retina during regeneration in adult newt eyes.
43.
Additionally, animal models suggest that the retinal pigment epithelium fails to phagocytose the outer rod segment discs that have been shed, leading to an accumulation of outer rod segment debris.
44.
It then proceeds to the cell membrane of the rod, where it is chaperoned to the Retinal Pigment Epithelium ( RPE ) by Interphotoreceptor Retinoid Binding Protein ( IRBP ).
45.
Knocking down levels of the CEP290 gene transcript resulted in dramatic suppression of ciliogenesis in retinal pigment epithelial cells in culture, proving just how important CEP290 is to cilia formation.
46.
The improper development of the retinal pigment epithelium ( RPE ), which in normal eyes absorbs most of the reflected sunlight, further increases glare due to light scattering within the eye.
47.
Phase I / II clinical trials involving retinal pigment epithelial ( RPE ) cells, derived from human embryonic stem cells, for the treatment of severe myopia were approved in February 2013.
48.
It takes up to 30 minutes for rhodopsin ( a retinal pigment sensitive to very low levels of light ) to recover after being bleached by exposure to bright ambient light.
49.
The fovea is located in a small avascular zone and receives most of its oxygen from the vessels in the choroid, which is across the retinal pigment epithelium and Bruch's membrane.
50.
Expression of SLC16A8 is confined to the retinal pigment epithelium and choroid plexus epithelia, where it is located on the basal membrane in contrast to MCT1 which is found on the apical membrane.
