In ribonucleotide reductase protein R1 from " Escherichia coli " this domain is located at the N terminus, and is composed mostly of subunits of ribonucleotide reductase.
42.
Misincorporated ribonucleotide induce DNA damage : It is not that the ribonucleotides do not prevent replication; actually, polDNA can tolerate templates with ribonucleotides, having normal early embryogenesis.
43.
Enzyme SAICAR synthetase, along with amino group from aspartate forms an amide bond to create N-succinyl-5-aminoimidazale-4-carboxamide ribonucleotide ( SAICAR ).
PurE, " N " 5-carboxyaminoimidazole ribonucleotide mutase, converts N5-CAIR to CAIR, the sixth step of " de novo " purine biosynthesis.
46.
Didox is used to inhibit ribonucleotide reductase M2 ( RRM2 ) which contributes to the cells resistance of the chemotherapy treatment resulting in a large number of relapse ( Wilson 2016 ).
47.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric systematic name of this enzyme class is "'3'- ribonucleotide phosphohydrolase " '.
48.
:nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H 2 O \ rightleftharpoons nicotinate D-ribonucleotide + diphosphate + ADP + phosphate
49.
They recognize the TEs, and this interaction results in formation of ribonucleotide protein ( RNP ) complexes, which travel along cytoskeleton filaments to the spine with the help of motor proteins.
50.
RNase H2 is a genome surveillance enzyme required for ribonucleotide removal : They found that ribonucleotide accumulation in genomic DNA of RNaseH2null mice implicates the RNaseH2 complex in the maintenance of genome integrity.
