| 41. | Mr . Calozza has a significant criminal background prior to 1984.
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| 42. | This will be his first significant participation in quite a while.
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| 43. | But industry experts disagree on whether the savings would be significant.
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| 44. | That decision is a significant change from ideas proposed last year.
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| 45. | Difficult budget decisions were made, often at significant political cost.
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| 46. | The change is highly significant, as an example will indicate.
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| 47. | I don't see anything significant in this ."
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| 48. | They found that key proteins between the two showed significant discrepancies.
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| 49. | Berger, the environmental attorney, said the change is significant.
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| 50. | That is a very significant challenge Mr . Ryan is facing.
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