Also, lipid rafts are enriched in sphingolipids such as sphingomyelin, which is typically elevated by 50 % compared to the plasma membrane.
42.
Other common R groups include phosphocholine, yielding a sphingomyelin, and various sugar monomers or dimers, yielding cerebrosides and globosides, respectively.
43.
This activates sphingomyelinase, an enzyme that catalyzes the hydrolysis of sphingomyelin to ceramide; sphingomyelinase activity has been observed in conjunction with cellular apoptosis.
44.
SMase is a member of the DNase I superfamily of enzymes and is responsible for breaking sphingomyelin ( SM ) down into phosphocholine and ceramide.
45.
SAMe is the universal methyl donor and is used for DNA methylation and to make membranes, choline, sphingomyelin and acetylcholine and other neurotransmitters.
46.
Sphingomyelin is a lipid constituent of cell membrane, and a dietary component being particularly abundant in milk, cheese, egg, and meat.
47.
*Marqibo ( Vincristine sulfate liposomes injection ) is a sphingomyelin / cholesterol liposome-encapsulated formulation of the FDA-approved anticancer drug vincristine.
48.
The organism is known to produce uncharacterized hemolytic agent ( s ), a neuraminidase and a phospholipase D ( PLD ) acting preferentially on sphingomyelin.
49.
A report working with human neutrophils proposed that G2A was a receptor for a phospholipid, lysophosphatidylcholine ( LPC ), and a Sphingomyelin, sphingosylphosphorylcholine.
50.
More specifically, it is synthesized at the ER, then is transferred by CERT to Golgi where it is converted to sphingomyelin ( SM ).
