| 41. | This tumor suppressor gene is a member of a nuclear histone / protein methyltransferase superfamily.
|
| 42. | Surprisingly, none of the 16 tumor-suppressor genes found so far have such a phosphate-removing role.
|
| 43. | The tumor-suppressor genes are one group of housekeeping genes.
|
| 44. | DCC can be considered a conditional tumour suppressor gene as well as a conditional oncogene.
|
| 45. | Mutations in either the TSC1 or TSC2 tumor suppressor gene are responsible for TSC disease.
|
| 46. | Dominant-negative mutations also occur in other tumor suppressor genes.
|
| 47. | Many of the pathway components recognized as tumor suppressor genes are mutated in human cancers.
|
| 48. | The first direct evidence for DCC as a tumour suppressor gene was published in 1995.
|
| 49. | Next Baylin and his colleagues looked at p16, a tumor-suppressor gene linked to many cancers.
|
| 50. | "APC " is classified as a tumor suppressor gene.
|