| 41. | This tumor suppressor gene is a member of a nuclear histone / protein methyltransferase superfamily.
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| 42. | Surprisingly, none of the 16 tumor-suppressor genes found so far have such a phosphate-removing role.
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| 43. | The tumor-suppressor genes are one group of housekeeping genes.
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| 44. | DCC can be considered a conditional tumour suppressor gene as well as a conditional oncogene.
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| 45. | Mutations in either the TSC1 or TSC2 tumor suppressor gene are responsible for TSC disease.
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| 46. | Dominant-negative mutations also occur in other tumor suppressor genes.
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| 47. | Many of the pathway components recognized as tumor suppressor genes are mutated in human cancers.
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| 48. | The first direct evidence for DCC as a tumour suppressor gene was published in 1995.
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| 49. | Next Baylin and his colleagues looked at p16, a tumor-suppressor gene linked to many cancers.
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| 50. | "APC " is classified as a tumor suppressor gene.
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