| 1. | Complications from argininosuccinic aciduria may include developmental delay and mental retardation.
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| 2. | Laboratory studies showed 3-hydroxyisobutyric aciduria and mild lactic acidosis.
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| 3. | Defective UMP synthase can result in orotic aciduria, a metabolic disorder.
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| 4. | -- Glutaric aciduria, or GA-1.
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| 5. | A UMP synthetase deficiency can result in a metabolic disorder called orotic aciduria.
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| 6. | Mutations in this gene have been shown to cause metaphyseal chondromatosis with aciduria.
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| 7. | Fewer than 20 cases of 3-methylglutaconic aciduria type I have been reported.
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| 8. | They also cause D-2-hydroxyglutaric aciduria and Ollier and Maffucci syndromes.
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| 9. | One mutation in patients with argininosuccinic aciduria occurs when glutamine 286 is mutated to arginine.
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| 10. | 3-Methylglutaconic aciduria, seems to be most prevalent amongst the Jewish population of Iraq.
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