| 1. | Where anatoxin had the highest activity efficacy and tubocurare the lowest.
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| 2. | *I enjoyed watching the external video about anatoxin-a.
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| 3. | Anatoxin-a binding to these nAchRs cause the same effects in neurons.
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| 4. | Studies have shown that some microorganisms are capable of degrading anatoxin-a.
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| 5. | In the same year JP Devlin and colleagues discovered the bicyclic secondary amine structure of anatoxin-a.
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| 6. | Many cases of wildlife and livestock deaths due to anatoxin-a have been reported since its discovery.
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| 7. | In mice, anatoxin-a also seriously impacted blood pressure and heart rate, and caused severe acidosis.
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| 8. | Acetylcholine on the other hand induced a much longer opening time of the receptor though anatoxin is more potent.
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| 9. | The results suggest that anatoxin derivatives would be helpful in understanding structure-activity relationships ( SAR ) for muscle nAChRs.
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| 10. | However, anatoxin-a binding is irreversible, and the anatoxin-a nAchR complex cannot be broken down by acetylcholinesterase.
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