| 1. | In translation, complementary tRNA anticodon sequences to mRNA codons.
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| 2. | The ribosome must discriminate between correct and incorrect codon-anticodon pairs.
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| 3. | An interesting example of A-minor is its role in anticodon recognition.
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| 4. | Cytoplasmic tRNA genes can be grouped into 49 families according to their anticodon features.
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| 5. | The reason is that the ribosome only sees the anticodon of the tRNA during translation.
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| 6. | The tRNA anticodon domain associates with the mRNA codon domain in the ribosomal A site.
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| 7. | This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA.
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| 8. | It is complementary to the anticodon of the tRNA that is a substrate of the tRNA synthetase under regulation.
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| 9. | Thus, the ribosome will not be able to discriminate between tRNAs with the same anticodon but linked to different amino acids.
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| 10. | Aminoacyl tRNA synthetases ( enzymes ) catalyze the bonding between specific tRNAs and the amino acids that their anticodon sequences call for.
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