| 1. | Chlorpromazine is used to treat schizophrenia and other acute psychotic diseases.
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| 2. | The first, chlorpromazine, was developed as a surgical anesthetic.
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| 3. | Chlorpromazine may be used as an antiemetic in dogs and cats.
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| 4. | Chlorpromazine has H1, M1, and ?1 receptor antagonist activity.
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| 5. | Chlorpromazine also reduces phenytoin levels and increases valproic acid levels.
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| 6. | These medications are also used to treat hiccups, along with chlorpromazine.
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| 7. | Promethazine, and subsequently chlorpromazine, were derived from fenethazine.
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| 8. | High doses of chlorpromazine can cause permanent shaking in muscles throughout the body.
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| 9. | Chlorpromazine has also been used in porphyria and as part of tetanus treatment.
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| 10. | Prochlorperazine and desferrioxamine may also interact with chlorpromazine to produce transient metabolic encephalopathy.
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