| 1. | Currently in the process of FDA approval is the injection of collagenase.
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| 2. | Collagenase " clostridium histolyticum " injection for Dupuytren's contracture.
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| 3. | The treatment with collagenase is different for the MCP joint and the PIP joint.
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| 4. | The collagenase is distributed across three injection points.
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| 5. | This leads to local inflammation through the signalling of synovial cells to produce metalloproteinases and collagenase
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| 6. | Collagenase is only used when the ECM scaffold product does not require an intact collagen structure.
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| 7. | At the same time, the cells begin making too little collagenase, the enzyme that destroys excess collagen.
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| 8. | Analysis of the primary structure of the gene sequence may thus be implicated in self-processing of the collagenase.
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| 9. | Collagenase solution is injected into the pancreatic duct which runs through the head, body and tail of the pancreas.
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| 10. | This powder can then be mixed with collagenase to form an ECM derived hydrogel ( self-healing hydrogels ).
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