| 1. | An electrophilic substitution reaction on benzene does not always result in monosubstitution.
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| 2. | In electrophilic substitution in aliphatic compounds, an electrophile displaces a functional group.
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| 3. | The alpha carbon then undergoes electrophilic substitution with bromine.
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| 4. | For instance, the page dealing with electrophilic substitution could benefit from showing a mechanism.
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| 5. | Indole undergoes electrophilic substitution, mainly at position 3 ( see diagram in right margin ).
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| 6. | However, electrophilic substitution is relatively facile at the 5-position, including nitration and halogenation.
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| 7. | A noteworthy exception occurs when electrophilic substitution is carried out in conditions sufficiently acidic to exhaustively protonate C3.
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| 8. | Imine generation is repeated a third time and the reaction concludes with a second electrophilic substitution to the other aromat.
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| 9. | This allows for strictosidine s formation under the subsequent ring closure via electrophilic substitution, as shown in the adjacent image.
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| 10. | Explain the Electrophilic substitution reaction in Durene . Preceding contribs ) 2005-07-12 23 : 55 : 45 CDT
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