| 1. | Water molecules form hydrogen bonds with each other and are strongly polar.
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| 2. | Polar solutes dissolve in polar solvents, forming polar bonds or hydrogen bonds.
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| 3. | The two characteristic hydrogen bonds are shown as green and purple lines
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| 4. | Hydrogen bonds play a key role in base pair binding and interaction.
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| 5. | Historically, the most favored model has been the hydrogen bond switching model.
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| 6. | The base pairs of a DNA strand are connected by hydrogen bonds.
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| 7. | When proton tunneling occurs, the hydrogen bond and covalent bonds are switched.
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| 8. | The hydrogen bond is often described as a strong electrostatic dipole-dipole interaction.
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| 9. | A well-defined pharmacophore model includes both hydrophobic volumes and hydrogen bond vectors.
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| 10. | Finally, the active site makes extensive hydrogen bonds with the DNA backbone.
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