| 1. | Many natural products, especially alkaloids, contain the imidazole ring.
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| 2. | Imidazole can be synthesized by numerous methods besides the Debus method.
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| 3. | The most important of these small molecules are pyrrole imidazole polyamides.
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| 4. | This ensured the differentiation of what will become the imidazole tail.
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| 5. | It acts as an antagonist similarly to other imidazoles like idazoxan.
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| 6. | Many compounds of industrial and technological importance contain imidazole derivatives.
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| 7. | The side products, carbon dioxide and imidazole, are relatively innocuous.
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| 8. | Imidazole has become an important part of many pharmaceuticals.
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| 9. | The imidazole nitrogen of a histidine side-chain is a common ligand.
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| 10. | The xanthine core of caffeine contains two fused rings, a pyrimidinedione and imidazole.
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