| 1. | Diltiazem has negative inotropic, chronotropic, and dromotropic effects.
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| 2. | Neurotransmitters receptors can either be inotropic or g protein coupled.
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| 3. | Hypoxia, acidosis, hyperkalemia are also negative inotropic agents.
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| 4. | Negatively inotropic agents weaken the force of muscular contractions.
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| 5. | Positively inotropic agents increase the strength of muscular contraction.
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| 6. | Its inotropic and chronotropic effects elevate diastolic blood pressure.
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| 7. | Inotropic receptors allow for ions to pass through when agonized by a ligand.
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| 8. | Agents that are dromotropic are often ( but not always ) inotropic and chronotropic.
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| 9. | Endothelin receptor activation mediates strong pulmonary vasoconstriction and positive inotropic effect on the heart.
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| 10. | Disopyramide has a negative inotropic effect on the ventricular myocardium, significantly decreasing the contractility.
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