| 1. | Modifications of lanosterol into other steroids are classified as steroidogenesis transformations.
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| 2. | Lanosterol is a key four-ringed intermediate in cholesterol biosynthesis.
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| 3. | In humans, lanosterol synthase is encoded by the LSS gene.
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| 4. | Finally, lanosterol is converted to cholesterol through a 19-step process.
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| 5. | Lanosterol can then be converted into other steroids such as cholesterol and ergosterol.
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| 6. | Because terbinafine prevents conversion of squalene to lanosterol, ergosterol cannot be synthesized.
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| 7. | Oxidosqualene cyclase then cyclizes squalene to form lanosterol.
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| 8. | Lanosterol can then be converted into other steroids, such as cholesterol and ergosterol.
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| 9. | Incorporation of lanosterol into viridin has been described.
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| 10. | Lanosterol synthase inhibitors are thought to lower LDL and VLDL cholesterol by a dual control mechanism.
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