| 1. | Transgenic gene knockout mice lacking MAPK1 have major defects in early development.
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| 2. | The major defects are multiple twins, as suggested by High-resolution transmission electron microscopy.
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| 3. | Major defects can result in the product's failure, reducing its marketability, usability or saleability.
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| 4. | Omission of planning from the purview of the district councils was another major defect.
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| 5. | The current system, although far superior to what went before, has two major defects.
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| 6. | Its major defect is equity : flat taxes bestow huge tax cuts on wealthy families.
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| 7. | And here as elsewhere the reader comes up against one of the book's major defects.
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| 8. | It is not a major defect, he said.
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| 9. | Suddenly, a major defect in the site title was discovered, and a new site was purchased.
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| 10. | :: : " In hindsight, I believe that the Court s opinion had two major defects.
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