| 1. | People with the disease have higher than normal levels of osteoclasts.
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| 2. | The cause of the disease is understood to be malfunctioning osteoclasts.
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| 3. | The two types of bisphosphonates work differently in killing osteoclast cells.
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| 4. | The osteoclasts dissolve the part of the bone that must change.
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| 5. | Pepstatin A suppresses the formation of multinuclear osteoclasts dose-dependently.
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| 6. | MicroRNA-223 also plays an essential role during osteoclast differentiation.
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| 7. | Bone-eating cells called osteoclasts have long been implicated in osteoporosis.
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| 8. | And they may also speed the action of osteoclasts, Rosen said.
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| 9. | Siris said alendronate works by coating surplus osteoclasts and suppressing their action.
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| 10. | Calcitonin lowers blood calcium and phosphorus mainly through its inhibition of osteoclasts.
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