| 1. | Yet the sperm can still get through the zona pellucida somehow.
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| 2. | Immunocontraception targeting the female gamete has focused on the zona pellucida.
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| 3. | N-acetylglucosamines on the zona pellucida normally promote sperm binding.
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| 4. | In 24 to 48 hours, the zona pellucida breaches.
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| 5. | Enzymes on the inner acrosomal membrane digest the zona pellucida.
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| 6. | After reaching the zona pellucida the actual acrosome reaction begins.
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| 7. | Acrosin digests the zona pellucida and membrane of the oocyte.
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| 8. | Upon stimulus, the acrosome releases its contents onto the zona pellucida.
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| 9. | It is here that lysis of the zona pellucida occurs.
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| 10. | This modification of the zona pellucida is known as the zona reaction.
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