| 1. | These include piperine, which gives black pepper its spicy taste.
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| 2. | The spiciness of black pepper is due to the chemical piperine.
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| 3. | It is one of the four diastereomeric geometric isomers of piperine.
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| 4. | Piperine remains the most potent and extensively researched bioenhancer till date.
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| 5. | In animal studies, piperine inhibited CYP450 enzymes involved in drug metabolism.
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| 6. | Besides the antibiotics rifampicin and isoniazid it contains piperine.
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| 7. | One example investigated is the potential for piperine to enhance the bioavailability of curcumin.
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| 8. | Piperine is being studied for its potential to affect bioavailability of other compounds in food.
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| 9. | Pepper gets its spicy heat mostly from piperine derived both from the outer fruit and the seed.
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| 10. | After the discovery of bioenhancer Piperine in 1979, a new chapter was added in medical science.
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