| 1. | This is presumably a function of urate's antioxidant properties.
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| 2. | Lesinurad enhances urate excretion by inhibition the tubular re-absorption.
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| 3. | They also have a tendency to form urate stones.
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| 4. | Broiler chickens with the toxicoinfectious form may also have diarrhea with excess urates.
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| 5. | Humans do have a gene for urate oxidase, but it is nonfunctional.
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| 6. | It is the product of the oxidation of uric acid by urate oxidase.
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| 7. | Lesinurad is an urate transporter inhibitor that has been approved to treat gout.
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| 8. | Glomerular filtration only accounts for 10 % to 20 % of urinary urate.
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| 9. | Urate stones are especially common after colon resection.
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| 10. | Dutch scientist Antonie van Leeuwenhoek first described the microscopic appearance of urate crystals in 1679.
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