| 1. | As vaccination gained acceptance, variolation gradually fell out of favor.
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| 2. | Various countries made variolation illegal, starting with Russia in 1805.
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| 3. | Variolation served as a natural precursor to the discovery of vaccination.
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| 4. | Variolation was prohibited in 1840, and vaccination was mandated in 1854.
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| 5. | The technique, call variolation, arrived in Europe in the early 1700s.
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| 6. | Because of associated deaths, variolation was declared illegal in the same year.
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| 7. | France was the last European country to embrace variolation.
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| 8. | The main arguments against variolation were on religious grounds.
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| 9. | The success of these variolations assured the British people that the procedure was safe.
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| 10. | Despite some opposition vaccination took over from variolation.
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